About us

Viesturs Baumanis , Dr. biol

Study Director
Phone: +371 67808219
E-mail: viesturs@biomed.lu.lv

Projects

• Molecular characterisation, epidemiology, immunogenetic aspects and clinical investigation of children tuberculosis causal agent
• The search for genetic factors underlying pathogenicity of nonviral tick-born infectious agents and the study of their properties for the development of individualised therapeutic approaches
• Characteristics and genetic diversity studies of pathogenic and relatively pathogenic mycobacteria present in Latvia
• Research, diagnostics, epidemiology, profilaxis and treatment of infectious pathogens resistant to antimicrobial agents
• Molecular genetic characterization of the population of Latvia
• Research of tubercolosis treatment and application of the research results in trearment and profilaxis
• Molecular and genetic reasearch of tick transfered diseases - ehrlichiosis, lyme borreliosis and tick-borne encephalitis in Latvia
• PathoGenoMics
• Emerging Diseases in a changing European environment
• Molecular analysis of Mycobacterium tuberculosis sensitive and resistant forms and appliaction of the results in tuberculosis treatment and profilaxis
• Molecular genetics research of Borrelia species and Borrelia burgdorferi types in territory of Latvia
• Mitochondrial DNA polymorphisms in Latvian enogenesis research
• Development of molecular biology methods for detection of resistent tuberculosis mycobacterium, approbation and appliement in tuberculosis treatment and profilaxis
• Early diagnostics of Lyme disease pathogen - Borrelia burgdorferi
• Detection, identification and typing of the Mycobacterium tuberculosis in the Baltic countries
• Genetic Aspects of Regulation of Water-Salt Metabolism

Publications

• International

• Prevalence and phylogenetic analysis of Babesia spp. in Ixodes ricinus and Ixodes persulcatus ticks in Latvia V Čapligina, Berzina, I., Bormane, A., Salmane, I., Vilks, K., A Kazarina, Bandere, D., V Baumanis, R Ranka , Experimental and Applied Acarology, 68 (3), pp. 325-336 , 2016
• Genotypic and phenotypic characteristics of aminoglycoside-resistant Mycobacterium tuberculosis isolates in Latvia. M Baušķenieks, I Pole, Skenders G, I Jansone, Broka L, Nodieva A, Ozere I, A Kalviša, R Ranka, V Baumanis , Diagn Microbiol Infect Dis. 81(3):177-82 , 2014
• Prevalence of tick-borne pathogens in ticks collected from migratory birds in Latvia. V Čapligina, Salmane I, Keišs O, K Vilks, Japina K, V Baumanis, R Ranka , Ticks Tick Borne Dis. Feb;5(1):75-81. , 2014
• Dynamics of telomere length in different age groups in a latvian population. E Zole, L Pliss, R Ranka, A Krūmiņa, V Baumanis , Curr Aging Sci. Dec;6(3):244-50. , 2013
• Point mutations associated with Leber hereditary optic neuropathy in a Latvian population. Aitullina A, Baumane K, Zalite S, R Ranka, E Zole, I Pole, Sepetiene S, Laganovska G, V Baumanis, L Pliss , Mol Vis. Nov 21;19:2343-51. , 2013
• Autochthonous canine babesiosis caused by Babesia canis canis in Latvia. Berzina I, V Čapligina, V Baumanis, R Ranka, Cirule D, Matise I , Vet Parasitol. Sep 23;196(3-4):515-8. , 2013
• Fibronectin-binding nanoparticles for intracellular targeting addressed by B. burgdorferi BBK32 protein fragments. R Ranka, I Petrovskis, I Sominska, J Bogans, R Brūvere, I Akopjana, V Ose-Klinklāva, I Timofējeva, K Brangulis, P Pumpēns, V Baumanis , Nanomedicine. Jan;9(1):65-73. , 2013
• Association between Anaplasma phagocytophilum seroprevalence in dogs and distribution of Ixodes ricinus and Ixodes persulcatus ticks in Latvia. Berzina I, V Čapligina, Bormane A, A Namiņa, V Baumanis, R Ranka, Granta R, Matise I , Ticks Tick Borne Dis. 1-2:83-8. , 2013
• Structure of an outer surface lipoprotein BBA64 from the Lyme disease agent Borrelia burgdorferi which is critical to ensure infection after a tick bite. K Brangulis, K Tārs, I Petrovskis, A Kazāks, R Ranka, V Baumanis , Acta Crystallogr D Biol Crystallogr. Jun;69(Pt 6):1099-107. , 2013
• Structural characterization of the Borrelia burgdorferi outer surface protein BBA73 implicates dimerization as a functional mechanism. K Brangulis, I Petrovskis, A Kazāks, V Baumanis, K Tārs , Biochem Biophys Res Commun. May 17;434(4):848-53. , 2013
• The link between mitochondrial DNA hypervariable segment I heteroplasmy and ageing among genetically unrelated Latvians L Pliss, Brakmanis A, R Ranka, Elferts D, A Krūmiņa, V Baumanis , Exp Gerontol. 46(7):560-8. , 2011
• Mitochondrial DNA origins of the Latvian clefting population Vieira AR, L Pliss, Pelena I, A Krūmiņa, V Baumanis, B Lāce , Mitochondrion 11(2):357-9. , 2011
• The link between mitochondrial DNA hypervariable segment I heteroplasmy and ageing among genetically unrelated Latvians. L Pliss, Brakmanis A., R Ranka, Elferts D., A Krūmiņa, V Baumanis , Exp Gerontol Jul;46(7):560-8. , 2011
• Y chromosome – a tool in infertility studies of Latvian population Puzuka A, Pronina N, Grinfelde I, Erenpreiss J, Lejins V, Bars J, L Pliss, Pelnena I, V Baumanis, A Krūmiņa , Genetika, Mar;47(3):394-400. , 2011
• Telomere length and mtDNA heteroplasmy in different age groups. R Ranka, L Pliss, E Zole, K Vilks, A Gustiņa, A Krūmiņa, V Baumanis , FEBS Journal 278 (Suppl. 1), p. 248. , 2011

• Local

• Cloning and expression of a recombinant immunogenic truncated BBK32 protein of Borrelia afzeli. R Ranka, V Čapligina, K Brangulis, Sondore V, V Baumanis , Acta Universitatis Latviensis 753: 33–42 , 2009
• Prevalence of varios Borrelia burgdorferi sensu lato species in Ixodes ticks in three Baltic countries. R Ranka, K Salmiņa, Zygutiene M, Morkunas B, Bormane A, V Baumanis , Acta Universitatis Latviensis 662: 7-15 , 2003
• The mitochondrial genome and human population studies. Pronina N, L Pliss, Lazdins M, V Baumanis, A Krūmiņa , Proc. Latvian Acad. Sci. 57(6): 199-208. , 2003
• Evaluation of the insertion sequence-6110-based polymerase chain reaction for detection of pathogenic mycobacteria. V Baumanis, I Jansone, Broka L, Nodieva A, Bratkovskis M, Tracevska T , Acta Universitatis Latviensis 662: 17-24 , 2003
• Ar hereditāro hemohromatozi saistītā gēna HFE mutācijas Latvijas poplulācijā. A Krūmiņa, Kroškina V, Keišs J, Mališeva B, V Baumanis , Zinātniskie raksti AML/RSU 134-138 , 2001
• Gene therapy, what it is? P Pumpēns, V Baumanis , Latvijas Ārsts 1: 37-40 , 2001
• Incidence of Borrelia Burgdorferi infected ticks in Latvia. V Baumanis, J Kloviņš, R Ranka, Vetcmane-Vetce K, Puzuka A, Lavrinoviča M, Bormane A, Kalniņa V , Proc. Latvian Acad. Sci. 4: 21-29 , 2001
• Incidence of Borrelia Burgdorferi infected ticks in Latvia and their molecular typing. V Baumanis, J Kloviņš, R Ranka, Vetcmane-Vetce K, Puzuka A, Lavrinoviča M, Bormane A, Kalniņa V , Proc. Latvian Acad. Sci. 55: 164-170 , 2001
• Gene therapy, real success V Baumanis, P Pumpēns , Latvijas Ārsts 3:40-43 , 2001
• Hereditary harmochromatosy cassing gene HFE mutations in Latvia. A Krūmiņa, Kroškina V, Mališeva B, V Baumanis , Zinātniskie raksti AML/RSU 103 , 2000
• Cystic fibrosis causing mutatios in Latvia. A Krūmiņa, Kroškina V, Švabe V, Krumina Z, Lazdinš M, V Baumanis , Zinātniskie raksti AML/RSU 102-105 , 2000
• Biological activity of recombinant a-human atrial natriuretic factor and its synthetic precursor phage fr coat – a-ANF fusion protein (CP/ANF). V Baumanis, I Jansone, Mishlakova N, Sietinsone I, Liepa S, Meness D, Klavina D, Berzins V , Proc. Latvian Acad. Sci. 5: 68-71. , 1993

• Patents

• Manufacturing method by bioengineering technology for producing human alpha natriuretic peptide. Berzins V, I Jansone, V Baumanis, Skangals A, T Kozlovska, Pusko P, E Grēns , Korean Patent, Nr. 95. 25099 , 1996

• Monographs

• Diagnostics of rifampicin resistant forms of tuberculosis in Latvia by amplification methods. /in "Genodiagnostics in Modern Medicine" pp. 286 - 287 Pancuka T, V Baumanis, I Jansone, Marga O, Broka L , Moscow: Venera-Press , 2000
• Isolation of a-human atrial natriuretic factor (a-ANF) from recombinant fusion protein. /in "Separations for Biotechnology 3." pp.73-78 Berzins V, V Baumanis, Skangals A, I Mandrika, I Jansone , SCI, Cambridge , 1994

• Conference thesis

• Crystal structure of the B. Burgdorferi outer surface protein of the paralogous gene family PFam5 R Ranka, K Brangulis, K Tārs, I Petrovskis, V Baumanis , Gordon Research Conferences frontiers of science, Venturi, ASV , 2014
• Diversity and spreed of Mycobacteium tuberculosis strains in Riga and its surroundings in Years 2009 - 2012 I Pole, I Jansone, Ģ.Šķenders, J.Trofimova, A.Nodieva, I.Ozere, V.Riekstiņa, P.Supply, E.Willery, S.Lecher, J.Storozenko, L.Vīksna, V.Leimane, R Ranka, V Baumanis , 35th Annunal Congress of the European Society of Mycobacteriology, Vīne, Austrija , 2014
• Successful creation of chimeric virus-like particles maintaining fibronectin-binding property from B.burgdorferi BBK32 protein R Ranka, I Petrovskis, I Sominska, K Brangulis, P Pumpēns, V Baumanis , XII International Jena Symposium on Tick-borne Diseases. Weimar, Vācija , 2013
• Study of B. burgdorferi outer membrane proteins by protein-protein interaction approach R Ranka, K Vilks, K Brangulis, I Petrovskis, V Čapligina, V Baumanis , 38th FEBS Congress, St.Petersburg, Krievija. , 2013
• Telomere length between mononuclear blood cells (MNC) and peripheral white blood cells (WBC) in context with population-specific mitochondrial (MT) lineages in a Latvian population ageing E Zole, L Pliss, R Ranka, A Krūmiņa, V Baumanis , 38th FEBS Congress, St.Petersburg, Krievija. , 2013
• Ērču encefalīta vīrusa RNS noteikšana migrējošo putnu ērcēs Latvijā Japiņa K, Keišs O, Salmane I, R Ranka, V Baumanis , RSU studentu zinātniskā konference, stenda referāts. , 2013
• Molecular genotyping confirms tuberculosis infetion transmission in household contacts as the main infection transmission route among children V Baumanis, Ozere I, I Jansone, Nodieva A, I Pole, M Baušķenieks, Skenders G , 34th Annual Congress of the European Society of Mycobacteriology. Florence, Itālija. Abstract book, p.76. , 2013
• M. tuberculosis infekcijas transmisijas biežuma noteikšana no infekcijas avota uz bērnu atkarībā no kontakta veida Nodieva A, I Jansone, Ozere I, Šķenders Ģ, Bobrikova O, Lauska Z, M Baušķenieks, Riekstiņa V, V Baumanis , RSU zinātniskā konference. Rīga, Latvija. Tēzes, p. 200. , 2013
• Interpreting of inexplicable findings of M.tuberculosis infection in children using genotyping of mycobacteria of matched child-infectious sources I Pole, Skenders G, Ozere I, Nodieva A, I Jansone, Broka L, M Baušķenieks, V Baumanis, Bobrikova O, Lauska Z, Zarovska E, Viksna L, Storozenko J, Rozentāle B , 22. European congress of Clinical Microbiology and infectious diseases, London , 2012
• Dissemination of Lyme disease agents in Eupope by migratory birds. R Ranka, V Čapligina, Keiss O, K Brangulis, K Vilks, V Baumanis , 1st Congress of Baltic Microbiologists, Riga. Book of abstracts, p. 06 , 2012
• Telomeres length variation in different age groups in Latvian population. L Pliss, E Zole, R Ranka, J Ķimsis, Aitullina A, A Krūmiņa, V Baumanis , Vth Interantional School of Molecular genetics “Changing genome”, Moscow-Zvenigorod. Abstracts p. 8. , 2012
• Genetic diversity and drug susceptibility pattern of M.tuberculosis strains from HIV positive patients in Latvia. I Pole, Nodieva A, I Jansone, Skenders G, Broka L, Riekstina V, Storozenko J, Rozentāle B, Leimane V, V Baumanis , Lietuvo gydytojo priedas, Vilnius, Lithuania. Final Program and abstract book, p 53-54 . , 2012
• Crystal structure of an outer surface protein BBA64 from Borrelai burgdorferi in comparison to BbCRASP-1. K Brangulis, K Tārs, I Petrovskis, R Ranka, V Baumanis , The FEBS Journal, v.279, S.1, p.467 , 2012
• The study of genetic factors in primary open-angle glaucoma patients in Latvia. R Ranka, A Gustiņa, Baumane K, L Pliss, Laganovska G, V Baumanis , The FEBS Journal, v.279, S.1, p.307 , 2012
• Molecular mitochondrial pathology in eye diseases. Aitullina A, Baumane K, L Pliss, Zalite S, Sepetiene G, Laganovska G, V Baumanis , The FEBS Journal, v.279, S.1, p.310 , 2012

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