Research Projects EU Structural funds 2014-2020




European Regional Development Fund (ERDF)

Operational Programme Growth and Employment

1.1.1 Specific Aid Objective To increase the research and innovative capacity of scientific institutions of Latvia and the ability to attract external financing, investing in human resources and infrastructure

First selection round projects
Assessment of magnitude and importance of vectorborne Babesiosis in Latvia: epidemiological and diagnostic approach
Diagnostic and immunoprotective potential of influenza virus hemagglutinin stalk peptide: generation of novel vaccine prototypes
Development of orphan G-protein coupled receptor peptidic ligand identification system
Molecular markers of pituitary tumor development, progression and therapy response
Investigation of interplay between multiple determinants influencing response to metformin: search for reliable predictors for efficacy of type 2 diabetes therapy
The impact of burial environmental microbiome on biomolecular archeology and the ancient tuberculosis research
Obtaining and characterization of virus-like particles of novel RNA phages
Development of new antimicrobial agents targeting Gram-positive bacterial sortase A
Molecular design of new luminescent compounds for diagnostic purposes
Long term effects of H.pylori eradication on Gastro intestinal tract microbiome and development of screening system for detection of extended-spectrum beta-lactamase coding genes within feces samples

Second selection round projects

Studies on Ribes plants, Cecidophyopsis mites and Blackcurrant Reversion virus for sustainable resistance breeding and cultivation of Ribes

Understanding the biology of the minimal residual disease after targeted therapy of BRAF mutant melanoma

Clinical utility of extracellular vesicle-enclosed human and microbial transcriptomes

RNA molecular determinants in development of pituitary adenoma

Role of miRNAs in the host-gut microbiome communication during metformin treatment in the context of metabolic disorders

The determination of rare inherited diseases' causative mechanisms using whole genome sequencing approach

Functional and genetic research of rare unidentitied neuromuscular disorders

Third selection round project

Interaction and dynamics of intestinal IgA and gut microbiome profile during antidiabetic therapy

Fourth selection round projects

Whole genome sequencing of tuberculosis for routine clinical use in Latvia: evidence-based design and concept evaluation

DECIDE - Development of a dynamic informed consent system for biobank and citizen science data management, quality control and integration

Usage of conservative borrelia protein as vaccine target

Testing of patient-derived stem cell extracellular vesicles loaded with drugs in a personalized lung-cancer on-chip platform (LoC4Ev)

An integrated population based Latvian genome reference and its applicability to personal risk estimation for metabolic traits

Fifth selection round projects

Identification of molecular determinants associated with the risk for various COVID-19 long term effects: a comprehensive cohort-based study in Latvian population

Enclosed lung on a chip system development suitable for respiratory disease research in BSL3 and microgravity systems (LoCBox)

The development of an efficient pilot-scale leghemoglobine production technology, based on recombinant Pichia pastoris and Kluyveromyceslactis fed-batch fermentations (BioHeme)

Large area deposition technologies of multifunctional antibacterial and antiviral nanocoatings

AI-improved organ on chip cultivation for personalised medicine (AImOOC) Activity Post-doctoral Research Aid

First selection round projects
Engineering of extracellular vesicles to transfer tumor suppressor miRNA to cancer cells
Structural and functional studies of Lyme disease agent Borrelia burgdorferi outer surface proteins to reveal the mechanisms of pathogenesis with the intention to create a new vaccine
sRNAflow – a tool for analysis of small RNA-seq data
Investigation of interaction of smoked dietary products with gut microbiome

Second selection round projects
Role of natural killer cells in the therapeutic efficacy of oncolytic measles virus 

Optimization of novel plant derived enzyme expression in microorganisms for biotechnological application

Combination of system and molecular biology approaches for discovery and characterization of plant enzymes for industrial processes

Identification of clinical subgroups of Type 2 diabetes mellitus and application of pharmacogenetics in development of personalized antidiabetic therapy

Third selection round projects

The role of “mitotic slippage” in the origin of amoeboid metastatic cell in therapy resistant cancers

Structural and kinetic studies of human carbonic anhydrases as multiple drug targets

Structural and functional studies of Ryegrass mottle virus-encoded proteins

Association of human intestinal and blood microbiome composition with general state of health and mortality within population of Latvia

 Fourth selection round projects

Structural studies of a Borrelia burgdorferi bacteriophage

Development of a bacterial microcompartment-based nanoreactor platform for metal-containing nanoparticle synthesis

Evaluation the potential of virus-like particles carrying carbonic anhydrase IX as anti-cancer vaccine Development of the R&D Infrastructure in Fields of Smart Specialisation and Strengthening of Institutional Capacity of Scientific Institutions 009
Infrastructure of the Latvian Biomedical Research and Study Center for the strengthening of research and technology transfer capacities in the fields of biomedicine and biotechnology 045
Development of a novel microfluidic device for label-free quantification of prostate cancer-derived extracellular vesicles and analysis of their RNA content (PROCEX) Support for International Cooperation Projects in Research and Innovation
Support for the integration of the Latvian Biomedical Research and Study Centre into the European Research Area and Infrastructure objects
European resercher Night in Latvia 2020



1.2.1. Specific Aid Objective To increase private sector investment in R&D Activity Support for Improvement of Technology Transfer System

Precision medicine test for the therapeutic decisions and monitoring of treatment response in breast cancer

Plant virus-derived vaccine technology platform

Development of anti-Lyme disease vaccine candidate

Development of anti-myostatin vaccine for promotion of livestock animal muscle growth

Dynamic human microbiome data platform and interpretation tool for personalized health recommendations




European Social Fund (ESF)

8.2.2. Strengthen academic staff of higher education institutions in areas of strategic specialisation. Third selection round.

Strengthening LU doctoral capacity under the new doctoral model

Quick links

Mājas lapas izstrādi finansēja ERAF aktivitātes projekts Nr. 2010/0196/2DP/ "Latvijas biomedicīnas pētījumu integrācija Eiropas zinātnes telpā".