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Pavels Zajakins , Dr. biol.
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Telefons: +371 67808200
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pz@magisters.net
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A. Linē grupa
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sRNAflow - rīks mazo RNS sekvenēšanas datu analīzei bioloģiskajos šķidrumos
Publikācijas
Starptautiskas
Antigen specificity and clinical significance of IgG and IgA autoantibodies produced in situ by tumor-infiltrating B cells in breast cancer. Garaud S, P Zajakins, Buisseret L, Rulle U, Siliņa K, de Wind A, den Eyden GV, Larsimont D, Willard-Gallo K,, A Linē , Frontiers in Immunology. 2018, 20 Nov. doi: 10.3389/fimmu.2018.02660. , 2018
Semen quality of young men from the general population in Baltic countries J Ērenpreiss, Punab, M., Zilaitiene, B., Hlevicka, S., P Zajakins, Matulevicius, V., Preiksa, R.T., Jørgensen, N. , Human Reproduction, 32 (6), pp. 1334-1340 , 2017
The prevalence of cancer-associated autoantibodies in patients with gastric cancer and progressive grades of premalignant lesions I Meistere, Werner S, P Zajakins, K Siliņa, U Rulle, A Pismennaja, Šantare D, Kikuste I, Isajevs S, Leja M, Kupčinskas L, Kupčinskas J, Jonaitis L, Wu CY, Brenner H,, A Linē, Z Kalniņa , Cancer Epidemiology Biomarkers Prev., Oct;26(10):1564-1574 , 2017
Depletion of carbonic anhydrase IX abrogates hypoxia-induced overexpression of stanniocalcin-1 in triple negative breast cancer cells E Zandberga, P Zajakins, A Ābols, D Pūpola, Trapencieris P, A Linē , Cancer Biol Ther, Jun 30:1-10 , 2017
Emerging blood-based biomarkers for detection of gastric cancer Z Kalniņa, I Meistere, Kikuste, I., Tolmanis, I., P Zajakins, A Linē , World Journal of Gastroenterology, 21 (41), pp. 11636-11653 , 2015
Survey of autoantibody responses against tumor-associated antigens in thyroid cancer. A Ābols, Ducena K, P Zajakins, K Siliņa, Z Kalniņa, L Sadovska, Tars J, Vilmanis J, Narbuts Z, Eglitis J, V Pīrāgs, A Linē , Cancer Biomark. 14(5):361-9 , 2014
Potential of tumour - associated autoantibodies as biomarkers for gastric cancer detection Z Kalniņa, I Meistere, P Zajakins, K Siliņa, A Pismennaja, M. Leja, A Linē , EACR-23 Biennial Congress of the European association for cancer research, Minhene, Vācija , 2014
Tumour-associated autoantibody signature for the early detection of gastric cancer P Zajakins, Ancāns G, K Siliņa, I Meistere, Z Kalniņa, Andrējeva D, E Endzeliņš, L Ivanova, A Pismennaja, Ruskule A, Doniņa S, Wex T, Malfertheiner P, Leja M, A Linē , Int J Cancer. Jan 1;132(1):137-47. , 2013
Sperm-associated Antigens as Targets for Cancer Immunotherapy: Expression Pattern and Humoral Immune Response in Cancer Patients. K Siliņa, P Zajakins, Z Kalniņa, L Ivanova, I Meistere, E Endzeliņš, A Ābols, Stengrēvics A, Leja M, Ducena K, Kozirovskis V, A Linē , J Immunother. 34(1):28-44. , 2011
Ranking-based kernels in applied biomedical diagnostics using a support vector machine V Jumuts, P Zajakins, Borisov A , Int J Neural Syst. Dec;21(6):459-73. , 2011
Evaluation of T7 and lambda phage display systems for survey of autoantibody profiles in cancer patients. Z Kalniņa, K Siliņa, I Meistere, P Zajakins, Rivosh A, A Ābols, Leja M, Minenkova O, Schadendorf D, A Linē , J Immunol Methods 334(1-2):37-50 , 2008
Alterations of pre-mRNA splicing in cancer. Z. Slucka, K Siliņa, P Zajakins, A Linē , Genes Chromosomes Cancer 42(4):342-57. , 2005
Vietēja mēroga
Antigen Reduction Applied to Support Vector Machine Classification for Melanoma-Related Diagnostics. V Jumuts, P Zajakins, A Linē , Polish J. of Environ. Stud 18(4a): 3-8 , 2009
Applying ANN ensembles to melanomas –related diagnostics on cancer patients. V Jumuts, P Zajakins, A Linē , Scientific Proceedings of Riga Technical University 5: 100-8 , 2008
Transcription factor NFATc3 isoforms in lymphoid cells. I Iņaškina, L Jackeviča, P Zajakins, Serfling E, Ē Jankevics , Proc. Latvian Acad. Sci. 57(1/2): 11-6 , 2003
Patenti
Gastric cancer biomarkers and methods of use thereof A Linē, K Siliņa, Z Kalniņa, P Zajakins , European Patent Register EP2620772 , 2012
Konferenču tēzes
Exploration of the potential of tumour - associated autoantibodies as biomarkers for gastric cancer detection Z Kalniņa, I Meistere, P Zajakins, K Siliņa, A Pismennaja, M. Leja, A Linē , 22nd United European Gastroenterology Week, Vīne, Austrij , 2014
Cancer autoantibodies as prognostic biomarkers. K Siliņa, P Zajakins, Ancans G, Z Kalniņa, I Meistere, A Pismennaja, Leja M, A Linē , 1st International Symposium on Immunotherapy, The Royal Society in London. Abstract book p22. , 2013
Autoantibody biomarkers for early detection and prognosis of gastric cancer K Siliņa, P Zajakins, Ancāns G, Z Kalniņa, I Meistere, A Pismennaja, Leja M, A Linē , 15th International Congress of Immunology (ICI), Milan, Italy , 2013
Cancer-associated autoantibody signatures for early diagnosis and prognosis of gastric cancer K Siliņa, P Zajakins, Ancāns G, Z Kalniņa, I Meistere, A Pismennaja, Leja M, A Linē , B Cell Development and Function Symposium, Keystone, CO, USA. Abstract Book, p121. , 2013
The relationship between senescence p21CIP1 and self-renewal protein OCT4 in the etoposide-treated embryonal carcinoma cells A Hūna, K Salmiņa, Jackson TR, P Zajakins, J Ērenpreisa , 23rd Wilhelm Benhard Workshop on the cell nucleus, Debrecen. Abstr. Book, p. 99. , 2013
The expression patterns of the opposite regulators OCT4A and P21CIP1 in the Etoposide-treated embryonal carcinoma cells. Visualising of senescent cells in vitro and in vivo. A Hūna, K Salmiņa, Jackson TR, P Zajakins, Huang S, J Ērenpreisa , Biogerontological Meetings at the Nencki Institute, Warsaw , 2012
Identification of autoantibody profiles in melanoma patients associated with the response to immunotherapy. K Siliņa, P Zajakins, Z Kalniņa, I Meistere, A Linē , 12th International Conference on Progress in Vaccination Against Cancer (PIVAC12). Nottingham, UK. Abstract book p30. , 2012
Diagnostic and prognostic relevance of tumour-associated autoantibody signatures in gastric cancer. P Zajakins, Ancāns G, K Siliņa, I Meistere, Z Kalniņa, Leja M, A Linē , EACR 22nd congress. Barcelona, Spain. Eur J Cancer, Sup 5, Vol 48, p.S212 , 2012
Exploration of autoantibody responses during MCA-induced carcinogenesis. I Meistere, L Sadovska, P Zajakins, A Pismennaja, Z Kalniņa, A Linē , 1st EATI and 3rd ERI-ICP conference on Death, Danger, Inflammation and Immunity. Paris. Abstracts p107. , 2012
Exosomal miRNA signature as potential biomarker for the early detection of non-small-cell lung cancer. Andrējeva D, E Zandberga, A Ābols, Kopeika U, Purkalne G, P Zajakins, A Linē , International society for extracellular vesicle 2012. Gothenburg, Sweden. Abstract Book, p25. , 2012
Prognostic and predictive value of autoantibody signatures in melanoma patients. P Zajakins, K Siliņa, Z Kalniņa, I Meistere, A Linē , 1st EATI and 3rd ERI-ICP conference on Death, Danger, Inflammation and Immunity. Paris, France, Abstracts, p117. , 2012
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Mājas lapas izstrādi finansēja ERAF 2.1.1.2. aktivitātes projekts Nr. 2010/0196/2DP/2.1.1.2.0/10/APIA/VIAA/004 "Latvijas biomedicīnas pētījumu integrācija Eiropas zinātnes telpā".