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2008 (Read 9272 times)
sharip
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2008
11.01.2008 at 15:13:35
 

Publikācijas 2008
 
1.      Hegazy UM, Tars K, Hellman U, Mannervik B. Modulating catalytic activity by unnatural amino acid residues in a GSH-binding loop of GST P1-1. J Mol Biol. 2008 Feb 22;376(3):811-26.
2.      Erenpreisa J, Ivanov A, Wheatley SP, Kosmacek EA, Ianzini F, Anisimov AP, Mackey M, Davis PJ, Plakhins G, Illidge TM. Endopolyploidy in irradiated p53-deficient tumour cell lines: Persistence of cell division activity in giant cells expressing Aurora-B kinase. Cell Biol Int  2008, 32: 1044-1056.
3.      Erenpreisa J and Cragg MS. Life-cycle features of tumour cells. P. Pontarotti (ed.), Evolutionary Biology from Concept to Application,_Springer-Verlag Berlin Heidelberg 2008, Chapter 4, pp. 61-70.
 
4.      Ivanov, M. Ivanova, J. Erenpreisa, S.V. Gloushen, T. Freivalds and M.S. Cragg. Image analysis of DNA repair and apoptosis in tumor cells with differing sensitivity to DNA damage. Alexei Katashev, Yuri Dekhtyar, Janis Spigulis (Eds.) 14th Nordic-Baltic Conference on Biomedical Engineering (NBS) 2008, Proceedings Vol. 20, pp. 524–527.  Springer-Verlag Berlin Heidelberg 2008. www.springerlink.com/index/q01u279103875026.pdf
 
5.      Freivalds J.,Rūmnieks J.,Ose V.,Renhofa R.,Kazāks A., High-level expression and purification of bacteriophage GA virus-like particles from yeast Saccharomyces cerevisae and Pichia pastoris, Acta Universitatis Latviensis, ser.biol. Biology,pp.75-85,2008
6.      Rūmnieks J.,Freivalds J.,Cielēns I.,Renhofa R.,Specificity of packaging mRNA in bacteriophage GA virus-like particles in yeast Saccharomyces cerevisiae, Acta Univerisatis Latviensis,ser.biol, 745, 145-154, 2008.
7.      Skrastina D.,Bulavaite A.,Sominskaya I.,Kovalevska L.,OseV.,Priede D. Pumpens P. Sasnauskas K., High immunogenicity of a hydrophilic component of the hepatitis B virus preS1 sequence exposed on the surface of three virus-like particle carriers, Vaccine,26,1972-1981,2008.
 
8.      Kalniņa Z, Siliņa K and Linē A. Autoantibody profiles as biomarkers for response to therapy and early detection of cancer Current Cancer Therapy Reviews, 2008, 4 (2):149-156.
9.      Kalniņa Z, Siliņa K, Meistere I, Zayakin P, Rivosh A, Ābols A, Leja M, Minenkova O, Schadendorf D and Linē A. Evaluation of T7 and Lambda phage display systems for survey of autoantibody profiles in cancer patients. J Immunol Methods, 2008 May 20;334(1-2):37-50.
10.      Jumutcs V, Zayakin P and Linē A. Applying ANN ensembles to melanomas –related diagnostics on cancer patients. Scientific Proceedings of Riga Technical University 2008. Computer Science, 2008 (5): 100-108.
11.      Zeltins A. Plant Virus Biotechnology Platforms for Expression of Medicinal Proteins. In: Medicinal Protein Engineering, Khudyakov Y., (Ed.), CRC Press, Boca Raton, London, N.Y., W.D.C., 2008, pp. 481-515.
 
12.      Jacobsson JA, Danielsson P, Svensson V, Klovins J, Gyllensten U, Marcus C, Schioth HB, Fredriksson R: Major gender difference in association of FTO gene variant among severely obese children with obesity and obesity related phenotypes. Biochem Biophys Res Commun 2008, 368(3):476-482.
 
 
13.      Jacobsson JA, Klovins J, Kapa I, Danielsson P, Svensson V, Ridderstrale M, Gyllensten U, Marcus C, Fredriksson R, Schioth HB: Novel genetic variant in FTO influences insulin levels and insulin resistance in severely obese children and adolescents. Int J Obes (Lond) 2008, 32(11):1730-1735.
 
14.      Mandrika I, Prusis P, Bergstrom J, Yahorava S, Wikberg JE: Improving the affinity of antigens for mutated antibodies by use of statistical molecular design. J Pept Sci 2008, 14(7):786-796.
15.      Prusis P, Lapins M, Yahorava S, Petrovska R, Niyomrattanakit P, Katzenmeier G, Wikberg JE: Proteochemometrics analysis of substrate interactions with dengue virus NS3 proteases. Bioorg Med Chem 2008, 16(20):9369-9377.
16.      Kazaks A., Balmaks R., Voronkova T., Ose V., Pumpens P. Melanoma vaccine candidates from chimeric hepatitis B core virus-like particles carrying a tumor-associated MAGE-3 epitope. Biotechnol J 3, 1429–1436, 2008
 
17.      Ulrich R., Gedvilaite A., Voronkova T., Kazaks A., Johne R., and Sasnauskas K. Polyomavirus-derived virus-like particles. In: Khudyakov, Y. (Ed.), Medicinal Protein Engineering, CRC Press 2008, pp. 249-275.  
 
18.      Zajakina A, Niedre-Otomere B, Alekseeva J, and Kozlovska T  Alphaviruses: Multiplicity of Vectors and Their Promising Application as Vaccines and Cancer Therapy Agents, In: Khudyakov, Y. (Ed.), Medicinal Protein Engineering, CRC Press 2008,  pp. 519-550.  
 
19.      Kazaks A., and Voronkova T. Papillomavirus-derived virus-like particles. In: Khudyakov, Y. (Ed.), Medicinal Protein Engineering, CRC Press 2008, pp. 277-297
 
20.      E.Alekseeva, I.Sominskaya, D.Skrastina, I.Egorova, E.Starodubova, E.Kushners, M.Mihailova, N.Petrakova, R.Bruvere, T.Kozlovskaya, M.Isaguliants, P.Pumpens. Enhancement of the expression of HCV core gene gives to enhancement to core-specific immune response in DNA immunization: advantages of the heterologous DNA prime, proteins boost immunization regiment. Genetic Vaccines and Therapy, 2008, submitted.
 
21.      E.Alekseeva, I.Sominskaya, R.Bruvere, V.Ose, A.Zajakina, T.Kozlovska. Expression of hepatitis C virus structural genes controlled by alphaviral recombinant replicons. LU Raksti. Bioloģija, 2008., pieņemts publikācijai.
 
22.      F.Arša, S.Ņikišins, L.Lapke, J.Storoženko, O.Savicka, B.Rozentāle, V.Ķūse. C vīrushepatīta genotipi Latvijas iedzīvotājiem un to korelācija ar ārstēšanas kursa ilgumu. – LU Raksti Bioloģija lp.297.
 
23.      Pumpens P., Ulrich R., Sasnauskas K., Kazaks A., Ose V., Grens E. Construction of novel vaccines on the basis of the virus-like particles: Hepatitis B virus proteins as vaccine carriers, In: Y.Khudyakov (Ed.). Medicinal Protein Engineering. CRC Press, Taylor & Francis Group, Boca Raton London, New York, 2008, pp. 205-248.
 
24.      Kalnina Z, Silina K, Bruvere R, Gabruseva N, Stengrevics A, Barnikol-Watanabe S, Leja M, Line A. Molecular characterisation and expression analysis of SEREX-defined antigen NUCB2 in gastric epithelium, gastritis and  gastric cancer. Eur J Hisopathol, in press.
 
25.      Dekhtyar Yu, Kacanovska A, Mezinskis G, Pumpens P, Renhofa R.  Attenuation spectrum of self-assembled system: semiconductor and virus-like nanoparticles. Biomedical Engineering, Proceedings of International onference. Kaunas University of Technology. Technologija, Kaunas, 2008, pp. 169-171.
 
26.      Iņaškina I., Šteinbergs J., Vasiļjeva I., 2008, Jauna prenatālās diagnostikas metode Latvijā trisomiju riska noteikšanai. Latvijas Ārsts, 64-67.
27.      Lāce B., Vasiljeva I., Dundure I., Barkane B., Akota I., Krumina A., 2008, Is SNPs in MSX1 gene playing a role in the development of cleft palate (CP) or clef lip/palate (CLP)?, European Journal of Human Genetics 16: 330.,
28.      Vasiljeva, Z. Kovalova, S. Nikulshin, O. Nikolajeva and S.Lejniece, 2008, Coagulopathy with FVIII deficiency and bleeding in a female patient,  Haemophilia, 14 (Suppl. 2): 106.
 
29.      Rabe B, Delaleau M, Bischof A, Sominskaya I, Pumpens P, Cazenave C, Castroviejo M, Kann M. Nuclear entry of hepatitis b virus capsids involve disintegration to protein dimers followed by nuclear reassociation to capsids. J. Biol. Chem., 2008, prepared.
 
30.      Ranka R., Baumanis V. Cloning and expression of immunogenic proteins of Lyme disease pathogen, Borrelia burgdorferi. 20th IUBMB International Congress of Biochemistry and Molecular Biology and 11th FAOBMB Congress. Kioto, Japāna. Abstracts, p. 203
31.      Ranka R., Brangulis K., Sondore V., Baumanis V. Recombinant BBK32 protein fragment in serodiagnosis of Lyme disease. FEBS jounal, 2008, v.275, S.1, p. 275.
 
32.      D.Pjanova, A.Molvens, L.Akseln, L.Engele, B.Streinerte, K.Azarjana and O.heisele. Identification of CDK4 R24H mutation-positive melanoma falily by analysis of early-onset melanoma patients in Latvia. Pieņemts publicēšanai: in  Melanoma Research, 2009.
33.      Ozolina S, Sinicka O,  Jankevics E, Inashkina I, Gorski B, Gronwald J, Lubinski J, Nasedkina T,    Fedorova O, Lyubchenko L, Tihomirova L. The 4154delA mutation carriers in the BRCA1 gene    share common ancestry.     Publicēts Familial Cancer. 2008 Dec 9. [Epub ahead of print]    PMID: 19067236
 
 
34.      Shastry A. Sedimbi SK, Rajalingam R, Nikitina Zake L, Rumba I, Wigzell H, Sanjeevi CB. Combination of KIR 2D and HLA-C1 (Asn80) confers susceptibility to type 1 diabetes in Latvians. Int J Immunogenet. 2008.Dec.35(6), pp439-46
 
 
35.      Inashkina I, Radovica I, Smeltere L, Vitols E, Jankevics E.  Case-control study of patients with essential tremor in Latvia. European Journal of Neurology. 15: 988-990.2008.
36.      Inashkina I, Radovica I, Smeltere L, Vitols E, Jankevics E.  An association between essential tremor and ETM2 locus in Latvian population. European Human Genetics Conference. May 31 – June 3, Barcelona, Spain. Abstracts. European Journal of Human Genetics Vol. 16:311.2008.
 
37.      Li G, Assudani DP, Line A, Cao F, Miles A, Rees RC and McArdle SEB. Identification of Metastasis Associated Antigen 1 (MTA1) by Serological Screening of Prostate Cancer cDNA Libraries. Open Biochem J. 2008; 2: 100–107.
38.      E. Salna, K. Siliņa, J. Šaripova, A. Linē, N. Sjakste. Kvercetīna un kemferola ietekme uz iNOS ekspresiju kontroles un LPS inducēta iekaisuma gadījumā Wistar līnijas žurku aknās. LU Akadēmiskajais apgāds „LU Raksti. Medicīna", Nr 735., 2008. gads
39.      Persson M., Tars K. &Liljas L. The capsid of the small RNA phage PRR1 is stabilized by metal ions. J.Mol.Biol. 2008. 383: 914-22.
40.      Plevka P., Tars K& Liljas L. Crystal packing of a bacteriophage MS2 coat protein mutant corresponds to octahedral particles. Protein Sci. 2008 10: 1731-9.
41.      Sominskaya I, Mihailova M, Jansons J, Legzdina D, Pumpens P, Arsha F, Keish J, Sondore V, Rozentale B, Viksna L. Epidemiological study of Hepatitis B virus genotypes in Latvia. 2008. Submitted to J.Clin.Microbiol.  
42.      Sendi H., Mehrab-Mohseni M., Shahraz S., Norder H., , Noorinayer B., Zali M.R., Pumpens P.,  Magnius L.O. CTL escape mutation of core protein are more frequent in strains of HBeAg negative patients with low viral load. 2008. Liver International, submitted.  
43.      Rabe B, Delaleau M, Bischof A, Sominskaya I, Pumpens P, Cazenave C, Castroviejo M, Kann M. Nuclear entry of hepatitis b virus capsids involve disintegration to protein dimers followed by nuclear reassociation to capsids. J. Biol. Chem., 2008, prepared.
44.      Dekhtyar Yu, Kachanovska A, Mezinskis G, Patmalnieks A, Pumpens P, Renhofa R. Self-assembled system of semiconductor and virus-like nanoparticles.  Functionalized Nanoscale Materials, Devices and Systems. Proceedingosf the NATO Advanced Study Institute on Functionalized Nanoscale Materials, Devices and Systems for Chem.-bio Sensors, Photonics, and Energy Generation and Storage, Sinaia, Romania, 4-15 June 007. Ed.: Vaseashta A, Mihailescu N. Springer, pp. 347-350.  
 
Patenti:
 
1.      Patent application 2008. 0292652 Virus-like particles comprising a fusion protein of the coat protein of AP 205 and an antigenic peptide. Renhofa R.,Pumpens P. Cielens I. & coworkers from Cytos Biotechnology
 
2.      Kazāks A., Freivalds J., Pumpēns P., Dišlers A. Rekombinants rauga Pichia pastoris celms cilvēka hepatīta B vīrusa (subtips ayw) nukleokapsīdu iegūšanai. Latvijas Republikas patents P-08-65 (02.10.2008 ekspertīzes lēmums).
 
 
3.      „Ekspresijas sistēma rekombinanto vīrusveidīgo daļiņu iegūšanai”; A.Dišlers, I. Sominska, A. Kazāks, I. Petrovskis, I. Zariņa. Patenta publikācijas datums: 20.02.2008. Pieteikuma datums: 13.12.2005. Numurs Nr. 13587.
 
4.      Tsimanis AY, Saripo A, Leonciks A , Kurbatska V, Rudevica Z. Human recombinant soluble CCR5 chemokine receptor. US Patent and and Trademark Office. Application No 61/065, Date 02/11/2008.
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